Intracytoplasmic sperm injection, or ICSI, involves injecting the husband’s single live sperm directly into the Centre of the wife’s egg. ICSI improves the chance of fertilization by 80%. ICSI is more effective than normal IVF and the technology evolved to achieve fertilization when male infertility is the issue or previous IVF cycles were not successful. ICSI overcomes m any of the barriers to fertilization and allows couples with little hope of achieving a successful pregnancy to obtain fertilized embryos.